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Stifel Upgrades Twilio to Buy, Citing Role as Key AI Communications Infrastructure

Summary
Investment firm Stifel upgraded Twilio to a Buy rating and raised its price target, highlighting the company's strengthening position as a foundational platform for AI-powered communications.
Stifel has upgraded Twilio (NYSE: TWLO) from Hold to Buy, raising its price target to $260 per share. The investment firm cited the company's successful restructuring and product focus, which it believes has positioned Twilio as essential infrastructure for the emerging era of artificial intelligence.
The AI Infrastructure Thesis
According to a note from Stifel analyst J. Parker Lane, customers are increasingly viewing Twilio "not as a channel vendor but as a foundational infrastructure layer for the era of AI." The firm highlighted the voice channel as a primary entry point, with its revenue growing 20% year-over-year last quarter, marking the sixth consecutive quarter of accelerating growth driven by AI adoption.
Stifel pointed to Twilio's strengthening competitive position, noting that approximately 90% of the Forbes AI 50 have built their platforms on the company's technology. This adoption by AI-native firms like Sierra and Bland.ai shows customers are "voting with their feet and their dollars to use Twilio as a provider of choice," the note stated.
Accelerating Financial Momentum
The upgrade is also supported by Twilio's improving financial performance. The company reported first-quarter organic growth of 16%, its fastest rate since 2022. This prompted management to raise its full-year 2026 organic growth guidance by 150 basis points to a range of 9.5% to 10.5%.
AdStifel noted that with key products like Voice, Branded Calling, and Conversational Intelligence each growing more than 100% year-over-year, the consensus revenue estimates for fiscal 2026 ($5.81 billion) and 2027 ($6.37 billion) appear to have an upward bias.
Improving Margins Address Investor Concerns
Stifel also highlighted significant improvements in Twilio's profitability and capital discipline. The company's first-quarter non-GAAP operating margin reached a record 19.8%.
Furthermore, stock-based compensation fell below 10% of revenue for the first time since Twilio's IPO. Stifel described this development as removing a "key bear-case overhang on dilution," addressing a long-standing concern among some investors.